Peran Rotational Tromboelastometry pada Perdarahan Postpartum
Abstract
Perdarahan postpartum atau postpartum hemorhage (PPH) merupakan penyebab paling tinggi dari kematian wanita di seluruh dunia. Penyebab terbanyak pada PPH adalah atonia uteri. Langkah penatalaksanaan PPH adalah mengatasi penyebab utama disertai penggantian cairan yang hilang dengan kristaloid, koloid maupun transfusi komponen darah. Tatalaksana transfusi darah masif pada PPH meningkatkan resiko reaksi transfusi seperti alergi, edema paru, dan anafilaksis. Untuk mengurangi jumlah transfusi darah diperlukan pemeriksaan yang cepat dan tepat mengenai data faktor koagulasi. Metode baru dengan point of care viskoelastik menggunakan alat Rotational Tromboelastometry (ROTEM) memungkinkan untuk menilai profil viskoelastik koagulasi darah dalam waktu yang singkat. Transfusi diberikan sesuai dengan hasil analisis ROTEM yang akan memberikan informasi mengenai jumlah platelet, fungsi platelet, dan ketersediaan fibrinogen. Penggunaan ROTEM bertujuan untuk goal directed transfusion therapy sehingga dapat menurunkan jumlah transfusi yang diberikan dan menurunkan morbiditas akibat transfusi darah. Penggunaan ROTEM pada penatalaksanaan PPH diharapkan bisa menjadi alternatif dalam panduan transfusi darah.
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Jurnal Anestesi Obstetri Indonesia
